This is part of the Med in Small Doses series, which aims to give you a snapshot of a disease or disorder. For information about the series, or common abbreviations click here.
A collection of symptoms not a diagnosis. Age: 16-30yo
Hallucination = false perception
Delusion = false belief
CFs: Delusions, Hallucinations, Disorganised speech & behaviour, thought alienation experiences, thought disorder.
PATHO: DA plays a role → Psychosis
- DA antagonists control SSx
- Schizophrenics have ↑ DA in Amygdala
- Amphetamines release DA & cause psychotic symptoms
RFs:
- Genetics,
- FHx,
- Age,
- Brain Abnormalities,
- Neurochemical changes,
- ↓ SES,
- Substance Abuse,
- Urban living
Tx: CBT, Family Therapy, ECT (on occasion).
Typical & Atypical antipsychotics. Haloperidol (DAR2 Antagonist) - controls psychosis and rapid sedation (esp. in conjunction with a benzodiazepine.
Risperdone (5-HT Blocker) - ↓ negative SSx
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